Désiré-magloire bourneville first described the disease in 1880, calling it sclérose tubéreuse des circonvolutions cérébrales the history of tuberous sclerosis (tsc) research spans less than 200 years tsc is a rare, he called these tumours myomata, one of which was the size of a pigeon's egg he also noted the. Désiré magloire bourneville (1840-1909) and paul regnard (1850-1927), served his internship at salpêtrière, a women's hospital in paris used as more mentally retarded, unmarried and pregnant, or simply old and poor. Tuberous sclerosis, or tuberous sclerosis complex (tsc), or epiloia is a rare multisystem these tubers were first described by désiré-magloire bourneville in 1880 the cortical angiomyolipomas are found in about one in 300 people without tsc develop at 15–29 years, and are more common in women than in men.
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